Researchers at the University of Toronto say they have successfully tested the use of machine learning models to guide the design of long-acting injectable drug formulations. The potential for machine ...

Early on, the drug substance (DS) manufacturer will provide a wealth of preliminary characterization data. And if the drug is active in early nonclinical and preclinical testing, a larger quantity of ...

Pharmaceutical companies follow strict quality standards, and if a drug’s stability falters at any point – whether during development, storage, or shipping, it can undo all the work that’s gone into ...

Moderna has tapped Swedish long-acting drug formulation company Nanexa to improve the delivery of up to five injectable therapies. The heavily back-loaded deal will see Moderna hand over just $3 ...

Predicting Bioequivalence During Generic Drug Formulation. Small variations in formulation can affect bioequivalence. However ...

Researchers develop an oil-based gel formula suitable for metered dosages of medication. There are many reasons why someone might find it difficult to swallow solid medications like pills and tablets.

AI/ML technologies are revolutionizing pharmaceutical formulation by optimizing excipient selection and predicting stability, reducing time and resources needed for development. Poor solubility of ...

Drug formulation is becoming increasingly complex. Poorly soluble APIs, personalized medicines, and advanced oral dosage forms require production methods that are scalable, reproducible, and precise.

A team of researchers has developed a new method to calculate and predict how drug molecules in molecular crystals arrange themselves under changing energetic conditions. For pharmaceutical companies, ...

CAMBRIDGE, MA -- About 60 percent of drugs on the market have hydrophobic molecules as their active ingredients. These drugs, which are not soluble in water, can be difficult to formulate into tablets ...

The media have been replete with reports of ways in which the pharmaceutical industry has been able to increase revenue from medications that have been available for decades. 1 We report a new ...