Our immune system relies on T cells to fight infections. But T cells don't just show up and react—first, they train, get a ...

The sugar glucose, which is the main source of energy in almost every living cell, has been revealed in a Stanford Medicine study to also be a master regulator of tissue differentiation - the process ...

The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

Every second, an adult generates around five million new blood cells to replace aging or dying ones, making the blood system a highly regenerative organ. These new blood cells are formed in the bone ...

A comprehensive map of aberrant hematopoiesis in people with acute myeloid leukemia defines specific cell states and potential therapeutic targets. The team used their reference map for normal ...

Mitochondria are essential for cell survival, repair, and adaptation. Not only do they generate most of the energy needed ...

A new study maps millions of cells across organs and shows how aging changes the body in coordinated and surprising ways.