Scientists discover hidden DNA scaffolding that forms before genes activate, revealing life’s blueprint is built before it begins.

Left: staining for H3K27me3, which marks inactive DNA, on a nucleus of a wildtype embryo consisting of two cells Right: staining for H3K27me3, which marks inactive DNA, on a nucleus of an embryo ...

Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.

Researchers from the Kind Group have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos. When an embryo is first formed after fertilization ...

An article by UAB professor Joan-Ramon Daban analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study ...

In a discovery that could redefine how we understand cellular resilience and adaptability, scientists have unlocked the secret interactions between a primordial inorganic polymer of phosphate known as ...

An illustration of multicolored tangle of threads within a small black sphere. A 3D illustration shows DNA packaged into the nucleus, scientists with the 4D Nucleome project are now building accurate ...